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1

Navigating the Island of Reil: how to understand the insular cortex

Wynford-Thomas, Ray, Powell, Rob

Journal:

Practical Neurology

Année:

2017

Langue:

english

Fichier:

PDF, 2.97 MB

english, 2017

2

Spontaneous de-differentiation correlates with extended lifespan in transformed thyroid epithelial cells: An epigenetic mechanism of tumour progression?

Jane A. Bond, Gro Oddweig Ness, Janet Rowson, Mircea Ivan, Denise White, David Wynford-Thomas

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 918 KB

english, 1996

3

Evidence against involvement of APC mutation in papillary thyroid carcinoma

Curtis, L., Wyllie, A.H., Shaw, J.J., Williams, G.T., Radulescu, A., DeMicco, C., Haugen, D.R.F., Varhaug, J.E., Lillehaug, J.R., Wynford-Thomas, D.

Journal:

European Journal of Cancer

Année:

1994

Langue:

english

Fichier:

PDF, 828 KB

english, 1994

4

A CHALLENGING CASE: SPINAL CORD SARCOIDOSIS

Wynford-Thomas, R., Smith, P.

Journal:

Journal of Neurology Neurosurgery & Psychiatry

Année:

2014

Langue:

english

Fichier:

PDF, 42 KB

english, 2014

5

10.1038/7827

Kipling, David, Wynford-Thomas, David, Jones, Chris J., Akbar, Arne, Aspinall, Richard, Bacchetti, Silvia, Blasco, Maria A., Broccoli, Dominique, DePinho, Ron A., Edwards, Dylan R., Effros, Rita B., H

Journal:

Nature Biotechnology

Année:

1999

Langue:

english

Fichier:

PDF, 88 KB

english, 1999

6

Control of Replicative Life Span in Human Cells: Barriers to Clonal Expansion Intermediate Between M1 Senescence and M2 Crisis

Bond, J. A., Haughton, M. F., Rowson, J. M., Smith, P. J., Gire, V., Wynford-Thomas, D., Wyllie, F. S.

Journal:

Molecular and Cellular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 2.41 MB

english, 1999

7

Neurological update: MOG antibody disease

Wynford-Thomas, Ray, Jacob, Anu, Tomassini, Valentina

Journal:

Journal of Neurology

Année:

2018

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2018

8

IN VIVO PHOTOINDUCTION OF METALLOTHIONEIN IN HUMAN SKIN BY ULTRAVIOLET IRRADIATION

ANSTEY, ALEXANDER, MARKS, RONALD, LONG, COLIN, NAVABI, HOSSEIN, PEARSE, ANTHONY, WYNFORD-THOMAS, DAVID, JASANI, BHARAT

Journal:

The Journal of Pathology

Année:

1996

Langue:

english

Fichier:

PDF, 573 KB

english, 1996

9

REVIEW ARTICLE. p53: GUARDIAN OF CELLULAR SENESCENCE

WYNFORD-THOMAS, DAVID

Journal:

The Journal of Pathology

Année:

1996

Langue:

english

Fichier:

PDF, 369 KB

english, 1996

10

Sporadicret-rearranged papillary carcinoma of the thyroid: a subset of slow growing, less aggressive thyroid neoplasms?

Soares, Paula, Fonseca, Elsa, Wynford-Thomas, David, Sobrinho-Simões, Manuel

Journal:

The Journal of Pathology

Année:

1998

Langue:

english

Fichier:

PDF, 267 KB

english, 1998

11

Cellular senescence and cancer

Wynford-Thomas, David

Journal:

The Journal of Pathology

Année:

1999

Langue:

english

Fichier:

PDF, 280 KB

english, 1999

12

Loss of responsiveness to transforming growth factor β (TGFβ) is tightly linked to tumorigenicity in a model of thyroid tumour progression

Jeremy P. Blaydes, David Wynford-Thomas

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 828 KB

english, 1996

13

Cytotoxic action of phorbol esters on human pancreatic cancer cells

Jane A. Bond, Andreas J. Gescher, Richard D. Verschoyle, Nicholas R. Lemoine, Rachel Errington, Marie Wiltshire, Paul J. Smith, David Wynford-Thomas

Journal:

International Journal of Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2007

14

Suppression of transformation and immortality in human/chinese hamster fibroblast hybrids—a model for suppressor gene isolation

D. Wynford-Thomas, J. A. Bond, H. Paterson

Journal:

International Journal of Cancer

Année:

1989

Langue:

english

Fichier:

PDF, 1.51 MB

english, 1989

15

Abnormalities of the EGF receptor system in human thyroid neoplasia

Nicholas R. Lemoine, Christine M. Hughes, William J. Gullick, Christopher L. Brown, David Wynford-Thomas

Journal:

International Journal of Cancer

Année:

1991

Langue:

english

Fichier:

PDF, 512 KB

english, 1991

16

Effect of serum growth factors and phorbol ester on growth and survival of human thyroid epithelial cells expressing mutant ras

Jane Bond, Tim Dawson, Nick Lemoine, David Wynford-Thomas

Journal:

Molecular Carcinogenesis

Année:

1992

Langue:

english

Fichier:

PDF, 776 KB

english, 1992

17

Stepwise transformation of primary thyroid epithelial cells by a mutant Ha-ras oncogene: An in vitro model of tumor progression

Jorge S. Burns, Jeremy P. Blaydes, Pat A. Wright, Louise Lemoine, Jane A. Bond, E. Dillwyn Williams, D. Wynford-Thomas

Journal:

Molecular Carcinogenesis

Année:

1992

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1992

18

Direct growth stimulation of normal human epithelial cells by mutant p53

Fiona S. Wyllie, Nick R. Lemoine, Claire M. Barton, Tim Dawson, Jane Bond, David Wynford-Thomas

Journal:

Molecular Carcinogenesis

Année:

1993

Langue:

english

Fichier:

PDF, 559 KB

english, 1993

19

Toxicity of phorbol esters for human epithelial cells expressing a mutant ras Oncogene

Tim Dawson, Jane Bond, Neil Eccles, David Wynford-Thomas

Journal:

Molecular Carcinogenesis

Année:

1993

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1993

20

Does telomere shortening drive selection for p53 mutation in human cancer?

Edward Bresnick, Nancy H. Colburn, Harold Moses, David Wynford-Thomas, Jane A. Bond, Fiona S. Wyllie, Christopher J. Jones

Journal:

Molecular Carcinogenesis

Année:

1995

Langue:

english

Fichier:

PDF, 545 KB

english, 1995

21

The polymerase chain reaction: Miracle or mirage? A critical review of its uses and limitations in diagnosis and research

Pat A. Wright, David Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1990

Langue:

english

Fichier:

PDF, 1.72 MB

english, 1990

22

In situ hybridization—principles and practice. J. M. Polak and J. O'D. MCGEE (Eds). Oxford University Press, Oxford, 1990.1711620419. of pages: 247. price: £25. ISBN: 0 19 261906 3

D. Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1990

Langue:

english

Fichier:

PDF, 124 KB

english, 1990

23

Oncogenes and anti-oncogenes; the molecular basis of tumour behaviour

D. Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1991

Langue:

english

Fichier:

PDF, 1.39 MB

english, 1991

24

Medical perspectives series: Oncogenes and tumour suppressor genes. F. Mcdonald and C. H. J. Ford. BIOS Scientific Publishers, Oxford, 1991. No. of pages: 101. Price: £11.95. ISBN: 1 872 748 55 4

D. Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1992

Langue:

english

Fichier:

PDF, 101 KB

english, 1992

25

P53 in tumour pathology: Can we trust immunocytochemistry?

David Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1992

Langue:

english

Fichier:

PDF, 188 KB

english, 1992

26

Mutations in familial cancer

P. A. Wright, D. Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1994

Langue:

english

Fichier:

PDF, 368 KB

english, 1994

27

Author's reply

D. Wynford-Thomas

Journal:

The Journal of Pathology

Année:

1995

Langue:

english

Fichier:

PDF, 138 KB

english, 1995

28

Telomerase activity and telomere length in thyroid neoplasia: biological and clinical implications

Paul Matthews, Christopher J. Jones, Julia Skinner, Michele Haughton, Catherine de Micco, David Wynford-Thomas

Journal:

The Journal of Pathology

Année:

2001

Langue:

english

Fichier:

PDF, 203 KB

english, 2001

29

Immunohistochemical localization of cell surface receptors using a novel method permitting simple, rapid and reliable LM/EM correlation

David Wynford-Thomas, Bharat Jasani, Geoffrey R. Newman

Journal:

Journal of Molecular Histology

Année:

1986

Langue:

english

Fichier:

PDF, 3.14 MB

english, 1986

30

Detection of theH-RASoncogene in human thyroid anaplastic carcinomas

B. M. Stringer, J. M. Rowson, M. H. Parkar, J. M. Seid, P. R. Hearn, D. Wynford-Thomas, S. Ingemansson, N. Woodhouse, M. H. Goyns

Journal:

Cellular and Molecular Life Sciences

Année:

1989

Langue:

english

Fichier:

PDF, 1.60 MB

english, 1989

31

Control of growth in the rat thyroid-an example of specific desensitization to trophic hormone stimulation

D. Wynford-Thomas, B. M. J. Stringer, H. R. Harach, E. D. Williams

Journal:

Cellular and Molecular Life Sciences

Année:

1983

Langue:

english

Fichier:

PDF, 726 KB

english, 1983

32

Investigation of putative control mechanisms for thyroid growth

David Wynford-Thomas, Bradley Michael John Stringer, Hector Ruben Harach, Edward Dillwyn Williams

Journal:

Virchows Archiv B Cell Pathology Zell-pathologie

Année:

1982

Langue:

english

Fichier:

PDF, 403 KB

english, 1982

33

Segregational fidelity of chromosomes in human thyroid tumour cells

E. M. Parry, H. Ulucan, F. S. Wyllie, D. Wynford-Thomas, J. M. Parry

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 288 KB

english, 1998

34

Characterisation of novel mutations in Cockayne syndrome type A and xeroderma pigmentosum group C subjects

Andrew J. Ridley, James Colley, David Wynford-Thomas, Christopher J. Jones

Journal:

Journal of Human Genetics

Année:

2005

Langue:

english

Fichier:

PDF, 202 KB

english, 2005

35

How may clonality be assessed in human tumours?

G.T. WILLIAMS, D. WYNFORD-THOMAS

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 744 KB

english, 1994

36

10.1038/39207

Wynford-Thomas, David, Kipling, David

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 158 KB

english, 1997

37

10.1038/71630

Faragher, Richard G.A., Wyllie, Fiona S., Jones, Christopher J., Skinner, Julia W., Haughton, Michele F., Wallis, Corrin, Wynford-Thomas, David, Kipling, David

Journal:

Nature Genetics

Année:

2000

Langue:

english

Fichier:

PDF, 451 KB

english, 2000

38

Optimisation of conditions for detection of activated oncogenes by transfection of NIH 3T3 cells

Lemoine, NR, Wynford-Thomas, V, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1987

Langue:

english

Fichier:

PDF, 669 KB

english, 1987

39

Loss of dependence on IGF-1 for proliferation of human thyroid adenoma cells

Williams, DW, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1988

Langue:

english

Fichier:

PDF, 879 KB

english, 1988

40

Ha-ras restriction fragment length polymorphisms in colorectal cancer

Wyllie, FS, Wynford-Thomas, V, Lemoine, NR, Williams, GT, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1988

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1988

41

Thyroid epithelial cell transformation by a retroviral vector expressing SV40 large T

Burns, JS, Lemoine, L, Lemoine, NR, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1989

Langue:

english

Fichier:

PDF, 1.62 MB

english, 1989

42

Structure and expression of nuclear oncogenes in multi-stage thyroid tumorigenesis

Wyllie, FS, Lemoine, NR, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1989

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1989

43

Papillary and follicular thyroid carcinomas show a different pattern of ras oncogene mutation

Wright, PA, Lemoine, NR, Mayall, ES, Wyllie, FS, Hughes, D, Williams, ED, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1989

Langue:

english

Fichier:

PDF, 430 KB

english, 1989

44

Characterisation of human thyroid epithelial cells immortalised in vitro by simian virus 40 DNA transfection

Lemoine, NR, Mayall, ES, Jones, T, Sheer, D, McDermid, S, Kendall-Taylor, P, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1989

Langue:

english

Fichier:

PDF, 2.01 MB

english, 1989

45

Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target

Hall-Jackson, CA, Jones, T, Eccles, NG, Dawson, TP, Bond, JA, Gescher, A, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1998

Langue:

english

Fichier:

PDF, 3.30 MB

english, 1998

46

Extensive allelic variation and ultrashort telomeres in senescent human cells

Baird, Duncan M., Rowson, Jan, Wynford-Thomas, David, Kipling, David

Journal:

Nature Genetics

Année:

2003

Langue:

english

Fichier:

PDF, 190 KB

english, 2003

47

Human thyroid cancer cells as a source of iso-genic, iso-phenotypic cell lines with or without functional p53

Wyllie, F S, Haughton, M F, Rowson, J M, Wynford-Thomas, D

Journal:

British Journal of Cancer

Année:

1999

Langue:

english

Fichier:

PDF, 483 KB

english, 1999

48

DNA damage checkpoint kinase Chk2 triggers replicative senescence

Wynford-Thomas, David, Brondello, Jean-Marc, Dulic, Vjekoslav, Gire, Véronique, Roux, Pierre

Journal:

The EMBO Journal

Année:

2004

Langue:

english

Fichier:

PDF, 356 KB

english, 2004

49

Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells

Ivan, Mircea, Bond, Jane A, Prat, Maria, Comoglio, Paolo Maria, Wynford-Thomas, David

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 768 KB

english, 1997

50

Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2

Blaydes, Jeremy P, Gire, Véronique, Rowson, Janet M, Wynford-Thomas, David

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 679 KB

english, 1997